He was strongly against co-education, commenting that "The difficulties involved in a common residence of hundreds of young men and women of immature character and marriageable age are very grave.The necessary police regulations are exceedingly burdensome." The committee persevered despite Eliot's skepticism.Lawrence Lowell still took a dim view of Radcliffe, maintaining that the time Harvard professors spent providing lectures to women distracted the faculty from their scholarship, and providing Radcliffe women access to research facilities and Harvard museums was – in his view – an unnecessary burden on the university's resources.He threatened to scuttle the relationship between the two institutions.
In subsequent years, on-going discussions with Harvard about admitting women directly into the university still came to a dead end, and instead Harvard and the Annex negotiated the creation of a degree-granting institution, with Harvard professors serving as its faculty and visiting body. Pres Eliot Commends the Work of the New Institution." The Globe said "Eliot stated that the percentage of graduates with distinction is much higher at Radcliffe than at Harvard" and that although "[i]t is to yet to be seen whether the women have the originality and pioneering spirit which will fit them to be leaders, perhaps they will when they have had as many generations of thorough education as men." In 1904, a popular historian wrote of the College's genesis: "...Indeed, the project proved to be a success, attracting a growing number of students.As a result, the Annex was incorporated in 1882 as the Society for the Collegiate Instruction of Women, with Elizabeth Cary Agassiz, widow of Harvard professor Louis Agassiz, as president.Students seeking admission to the new women's college were required to sit for the same entrance examinations required of Harvard students. Because the institution was housed with a private family, generous mothering was given to the girls when they needed it." Moving on from the little house, in the first two decades of the 20th century Radcliffe championed the beginnings of its own campus consisting of the Radcliffe Yard and the Radcliffe Quadrangle in Cambridge, Massachusetts, not far from that of Harvard.By 1896, the Globe could headline a story: "Sweet Girls. The original Radcliffe gymnasium and library, and the Bertram, Whitman, Eliot, and Barnard dormitories were constructed during this period.